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Ageing-related Papers

Highly Cited Papers on Ageing and Age-related Diseases

Note: This compilation is work in progress. Please email us (jsuehnel@fli-leibniz.de) if you are aware of papers that should be included in the list. Currently, the lower threshold is a total number of 1000 citations according to Google Scholar (GS). We have also analyzed the Web of Science (WoS) data but are obviously not allowed to make these data freely accessible according to the Thomson Reuters policy. Except for very few cases the number of GS citations is higher than the related WoS value. To get a more quantitative impression have a look on a plot of the correlation between GS and WoS data. The Date of Publication was obtained from PubMed. For older publications only the month is indicated. In this case the 1st day of the corresponding month was used. The Time Since Publication was calculated using Wolfram Alpha.
Link icons: PubMed = PubMed, Journal = Journal, PDF = Local PDF file
# Author(s) Title Journal Year Volume Pages Authors‘s Countries Links Free Article Subscription Required Publication Date Time Since Publication (Years) Times Cited - Total (Google Scholar) Times Cited - Per Year (Google Scholar) Date of Analysis Comments
1 McKhann G, Drachman D, Folstein M, Katzman R, Price D, Stadlan EM. Clinical diagnosis of Alzheimer‘s disease: Report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer‘s Disease. Neurology. 1984 34(7) 939-44 USA PUBMED JOURNAL PDF 01/07/1984 32.01 24029 751 06/07/2016
2 Braak H, Braak E. Neuropathological stageing of Alzheimer-related changes. Acta Neuropathol. 1991 82(4) 239-59 Europe (Germany) PUBMED JOURNAL + 01/04/1991 25.26 8930 353 06/07/2016
3 Kim NW, Piatyszek MA, Prowse KR, Harley CB, West MD, Ho PL, Coviello GM, Wright WE, Weinrich SL, Shay JW. Specific association of human telomerase activity with immortal cells and cancer. Science. 1994 266(5193) 2011-5 USA PUBMED JOURNAL + 23/12/1994 21.55 7497 348 12/07/2016
4 Katz S, Ford AB, Moskowitz RW, Jackson BA, Jaffe MW. Studies of illness in the aged. The index of ADL: A standardized measure of biological and psychosocial function. JAMA. 1963 185 914-9 PUBMED JOURNAL + 21/09/1963 50.55 8762 132 12/07/2016
5 Hardy J, Selkoe DJ. The amyloid hypothesis of Alzheimer‘s Disease: Progress and problems on the road to therapeutics. Science. 2002 297(5580) 353-6 USA PUBMED JOURNAL + 19/07/2002 13.98 8986 643 12/07/2016
6 Kessler RC, Berglund P, Demler O, Jin R, Merikangas KR, Walters EE. Lifetime prevalence and age-of-onset distributions of DSM-IV disorders in the National Comorbidity Survey Replication. Arch Gen Psychiatry. 2005 62(6) 593-602 USA PUBMED JOURNAL PDF 01/06/2005 11.11 10092 908 12/07/2016
7 Murray CJ, Lopez AD. Alternative projections of mortality and disability by cause 1990-2020: Global burden of disease study. Lancet. 1997 10(5) 594-605 Europe (Switzerland), USA PUBMED JOURNAL + 24/05/1997 19.13 7416 388 12/07/2016
8 Corder EH, Saunders AM, Strittmatter WJ, Schmechel DE, Gaskell PC, Small GW, Roses AD, Haines JL, Pericak-Vance MA. Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer‘s disease in late onset families. Science. 1993 261(5123) 921-3 USA PUBMED JOURNAL + 13/08/1993 22.91 6708 293 12/07/2016
9 Harman D. Aging: A theory based on free radical and radiation chemistry. J Gerontol. 1956 11(3) 298-300 USA PUBMED JOURNAL + 01/07/1956 57.78 6945 96 12/07/2016
10 Petersen RC, Smith GE, Waring SC, Ivnik RJ, Tangalos EG, Kokmen E. Mild cognitive impairment: Clinical characterization and outcome. Arch Neurol. 1999 56(3) 303-8 USA PUBMED JOURNAL + 01/03/1999 17.39 7057 406 20/07/2016
11 Ames BN, Shigenaga MK, Hagen TM. Oxidants, antioxidants and the degenerative diseases of aging. Proc Natl Acad Sci U S A. 1993 90(17) 7915-22 USA PUBMED JOURNAL PDF 01/09/1993 20.61 5447 264 20/07/2016
12 Droege W. Free radicals in the physiological control of cell function. Physiol Rev. 2002 82(1) 47-95 Europe (Germany) PUBMED JOURNAL PDF 01/01/2002 14.55 7214 496 20/07/2016
13 Durnin JV, Womersley J. Body fat assessed from total body density and its estimation from skinfold thickness: Measurements on 481 men and women aged from 16 to 72 years. Br J Nutr. 1974 32(1) 77-97 Europe (UK) PUBMED JOURNAL PDF 01/07/1974 42.12 6129 146 12/08/2016
14 Lewington S, Clarke R, Qizilbash N, Peto R, Collins R; Prospective Studies Collaboration. Age-specific relevance of usual blood pressure to vascular mortality: A meta-analysis of individual data for one million adults in 61 prospective studies. Lancet. 2002 360(9349) 1903-13 Europe (UK) PUBMED JOURNAL + 14/12/2002 13.63 6994 513 01/08/2016
15 Hayflick L, Moorhead PS. The serial cultivation of human diploid cell strains. Exp Cell Res. 1961 25 585-621 USA PUBMED JOURNAL + 01/12/1961 54.36 6136 113 11/08/2016
16 Polymeropoulos MH, Lavedan C, Leroy E, Ide SE, Dehejia A, Dutra A, Pike B, Root H, Rubenstein J, Boyer R, Stenroos ES, Chandrasekharappa S, Athanassiadou A, Papapetropoulos T, Johnson WG, Lazzarini AM, Duvoisin RC, Di Iorio G, Golbe LI, Nussbaum RL. Mutation in the alpha-synuclein gene identified in families with Parkinson‘s disease. Science. 1997 276(5321) 2045-7 Europe (Greece, Italy), USA PUBMED JOURNAL + 27/06/1997 19.12 5759 301 11/08/2016
17 Finkel T, Holbrook NJ. Oxidants, oxidative stress and the biology of ageing. Nature. 2000 408(6809) 239-47 USA PUBMED JOURNAL + 09/11/2000 15.75 6390 406 11/08/2016
18 Bartus RT, Dean RL 3rd, Beer B, Lippa AS. The cholinergic hypothesis of geriatric memory dysfunction. Science. 1982 217(4558) 408-14 USA PUBMED JOURNAL + 30/07/1982 34.04 5185 152 12/08/2016
19 Hayflick L. The limited in vitro lifetime of human diploid cell strains. Exp Cell Res. 1965 37 614-36 USA PUBMED JOURNAL + 01/03/1965 51.45 5110 99 12/08/2016
20 Podsiadlo D, Richardson S. The timed "Up & Go": A test of basic functional mobility for frail elderly persons. J Am Geriatr Soc. 1991 39(2) 142-8 Canada PUBMED JOURNAL + 01/02/1991 25.52 6865 269 08/08/2016
21 Hughes CP, Berg L, Danziger WL, Coben LA, Martin RL. A new clinical scale for the staging of dementia. Br J Psychiatry. 1982 140 566-72 USA PUBMED JOURNAL + 01/06/1982 34.20 5360 157 12/08/2016
22 Hughes AJ, Daniel SE, Kilford L, Lees AJ. Accuracy of clinical diagnosis of idiopathic Parkinson‘s disease: A clinico-pathological study of 100 cases. J Neurol Neurosurg Psychiatry. 1992 55(3) 181-4 Europe (UK) PUBMED JOURNAL PDF 01/03/1992 24.45 6112 250 12/08/2016
23 Tinetti ME, Speechley M, Ginter SF. Risk factors for falls among elderly persons living in the community. N Engl J Med. 1988 319(26) 1701-7 USA PUBMED JOURNAL + 29/12/1988 27.62 5515 200 12/08/2016
24 Selkoe DJ. Alzheimer‘s disease: Genes, proteins, and therapy. Physiol Rev. 2001 81(2) 741-66 USA PUBMED JOURNAL PDF 01/04/2001 15.38 5179 337 16/08/2016
25 Feldman HA, Goldstein I, Hatzichristou DG, Krane RJ, McKinlay JB. Impotence and its medical and psychosocial correlates: Results of the Massachusetts Male Aging Study. J Urol. 1994 151(1) 54-61 USA PUBMED JOURNAL + 01/01/1994 22.62 4841 214 16/08/2016
26 Kang J, Lemaire HG, Unterbeck A, Salbaum JM, Masters CL, Grzeschik KH, Multhaup G, Beyreuther K, Müller-Hill B The precursor of Alzheimer‘s disease amyloid A4 protein resembles a cell-surface receptor. Nature. 1987 325(6106) 733-6 Australia, Europe (Germany) PUBMED JOURNAL + 19/02/1987 29.52 4530 153 16/08/2016
27 Harley CB, Futcher AB, Greider CW. Telomeres shorten during aging of human fibroblasts. Nature. 1990 345(6274) 458-60 Canada, USA PUBMED JOURNAL + 31/05/1990 26.21 4922 188 16/08/2016
28 Bodnar AG, Ouellette M, Frolkis M, Holt SE, Chiu CP, Morin GB, Harley CB, Shay JW, Lichtsteiner S, Wright WE. Extension of life-span by introduction of telomerase into normal human cells. Science. 1998 279(5349) 349-52 USA PUBMED JOURNAL + 16/01/1998 18.58 4712 254 16/08/2016
29 Glenner GG, Wong CW. Alzheimer‘s disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein. Biochem Biophys Res Commun. 1984 120(3) 885-90 USA PUBMED JOURNAL + 16/05/1984 32.28 4633 144 16/08/2016
30 Blessed G, Tomlinson BE, Roth M. The association between quantitative measures of dementia and of senile change in the cerebral grey matter of elderly subjects. Br J Psychiatry. 1968 114(512) 797-811 Europe (UK) PUBMED JOURNAL + 01/07/1968 48.13 4420 92 17/08/2016
31 Dimri GP, Lee X, Basile G, Acosta M, Scott G, Roskelley C, Medrano EE, Linskens M, Rubelj I, Pereira-Smith O, Peacocke M, Campisi J. A biomarker that identifies senescent human cells in culture and in aging skin in vivo. Proc Natl Acad Sci U S A. 1995 92(20) 9363-7 USA PUBMED JOURNAL PDF 26/09/1995 20.89 4917 235 17/08/2016
32 Cummings JL, Mega M, Gray K, Rosenberg-Thompson S, Carusi DA, Gornbein J. The Neuropsychiatric Inventory: Comprehensive assessment of psychopathology in dementia. Neurology. 1994 44(12) 2308-14 USA PUBMED JOURNAL + 01/12/1994 21.71 5050 233 17/08/2016
33 O‘Leary DH, Polak JF, Kronmal RA, Manolio TA, Burke GL, Wolfson SK Jr. Carotid-artery intima and media thickness as a risk factor for myocardial infarction and stroke in older adults. Cardiovascular Health Study Collaborative Research Group. N Engl J Med. 1999 340(1) 14-22 USA PUBMED JOURNAL PDF 07/01/1999 17.61 4567 259 17/08/2016
34 Langston JW, Ballard P, Tetrud JW, Irwin I. Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis. Science. 1983 219(4587) 979-80 USA PUBMED JOURNAL + 25/02/1983 33.84 4128 122 17/08/2016
35 Goate A, Chartier-Harlin MC, Mullan M, Brown J, Crawford F, Fidani L, Giuffra L, Haynes A, Irving N, James L, Mant R, Newton P, Rooke K, Roques P, Talbot C, Pericak-Vance M, Roses A, Williamson R, Rossor M, Owen M, Hardy J Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer‘s Disease. Nature. 1991 349(6311) 704-6 Europe (UK), USA PUBMED JOURNAL + 21/02/1991 25.49 4164 163 17/08/2016
36 Lindahl T. Instability and decay of the primary structure of DNA. Nature. 1993 362(6422) 709-15 Europe (UK) PUBMED JOURNAL + 22/04/1993 23.32 4209 180 17/08/2016
37 Spillantini MG, Schmidt ML, Lee VM, Trojanowski JQ, Jakes R, Goedert M. Alpha-synuclein in Lewy bodies. Nature. 1997 388(6645) 839-40 Europe (UK), USA PUBMED JOURNAL + 28/08/1997 18.97 4382 231 18/08/2016
38 Ames BN. Dietary carcinogens and anticarcinogens. Oxygen radicals and degenerative diseases. Science. 1983 22(4617) 256-64 USA PUBMED JOURNAL + 23/09/1983 32.90 3826 116 18/08/2016
39 Strittmatter WJ, Saunders AM, Schmechel D, Pericak-Vance M, Enghild J, Salvesen GS, Roses AD. Apolipoprotein E: High-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease. Proc Natl Acad Sci U S A. 1993 90(5) 1977-81 USA PUBMED JOURNAL PDF 01/03/1993 23.47 3789 161 19/08/2016
40 Rowe JW, Kahn RL. Successful aging. Gerontologist. 1997 73(4) 433-40 USA PUBMED JOURNAL + 01/08/1997 19.05 5050 265 19/08/2016
41 Masters CL, Simms G, Weinman NA, Multhaup G, McDonald BL, Beyreuther K. Amyloid plaque core protein in Alzheimer disease and Down syndrome. Proc Natl Acad Sci U S A. 1985 82(12) 4245-9 Australia, Europe (Germany) PUBMED JOURNAL PDF 01/06/1985 31.32 3869 124 22/08/2016
42 Hsiao K, Chapman P, Nilsen S, Eckman C, Harigaya Y, Younkin S, Yang F, Cole G. Correlative memory deficits, A beta elevation, and amyloid plaques in transgenic mice. Science. 1996 274(5284) 99-102 Europe (UK), USA PUBMED JOURNAL + 04/10/1996 19.88 3777 190 22/08/2016
43 Pfeiffer E. A short portable mental status questionnaire for the assessment of organic brain deficit in elderly patients. J Am Geriatr Soc. 1975 23(10) 433-41 USA PUBMED JOURNAL + 01/10/1975 40.89 4166 102 22/08/2016
44 McKeith IG, Galasko D, Kosaka K, Perry EK, Dickson DW, Hansen LA, Salmon DP, Lowe J, Mirra SS, Byrne EJ, Lennox G, Quinn NP, Edwardson JA, Ince PG, Bergeron C, Burns A, Miller BL, Lovestone S, Collerton D, Jansen EN, Ballard C, de Vos RA, Wilcock GK, Jellinger KA, Perry RH. Consensus guidelines for the clinical and pathologic diagnosis of dementia with Lewy bodies (DLB): Report of the consortium on DLB international workshop. Neurology. 1996 47(5) 1113-24. Europe (UK) PUBMED JOURNAL + 01/11/1996 19.81 3693 186 23/08/2016
45 Mirra SS, Heyman A, McKeel D, Sumi SM, Crain BJ, Brownlee LM, Vogel FS, Hughes JP, van Belle G, Berg L. The Consortium to establish a registry for Alzheimer‘s Disease (CERAD). Part II. Standardization of the neuropathologic assessment of Alzheimer‘s disease. Neurology. 1991 41(4) 479-86 USA PUBMED JOURNAL + 01/04/1991 25.39 3661 144 23/08/2016
46 Kitada T, Asakawa S, Hattori N, Matsumine H, Yamamura Y, Minoshima S, Yokochi M, Mizuno Y, Shimizu N. Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism. Nature. 1998 392(6676) 605-8 Japan PUBMED JOURNAL + 09/04/1998 18.31 3799 207 01/08/2016
47 Ferri CP, Prince M, Brayne C, Brodaty H, Fratiglioni L, Ganguli M, Hall K, Hasegawa K, Hendrie H, Huang Y, Jorm A, Mathers C, Menezes PR, Rimmer E, Scazufca M; Alzheimer‘s Disease International Global prevalence of dementia: A Delphi consensus study. Lancet. 2005 366(9503) 2112-7 Australia, Brazil, China, Europe (Sweden, UK), Japan, USA PUBMED JOURNAL + 17/12/2005 10.68 4593 430 23/08/2016
48 Braak H, Del Tredici K, Rüb U, de Vos RA, Jansen Steur EN, Braak E. Staging of brain pathology related to sporadic Parkinson‘s disease. Neurobiol Aging. 2003 24(2) 197-211 Europe (Germany, Netherlands) PUBMED JOURNAL + 01/03/2003 13.48 4648 345 23/08/2016
49 Petersen RC, Doody R, Kurz A, Mohs RC, Morris JC, Rabins PV, Ritchie K, Rossor M, Thal L, Winblad B. Current concepts in mild cognitive impairment. Arch Neurol. 2001 58(12) 1985-92 USA PUBMED JOURNAL + 01/12/2001 14.72 3998 272 23/08/2016
50 Saunders AM, Strittmatter WJ, Schmechel D, George-Hyslop PH, Pericak-Vance MA, Joo SH, Rosi BL, Gusella JF, Crapper-MacLachlan DR, Alberts MJ, et al. Association of apolipoprotein E allele epsilon 4 with late-onset familial and sporadic Alzheimer‘s disease. Neurology. 1993 43(8) 1467-72 USA, Canada PUBMED JOURNAL + 01/08/1993 23.06 3432 149 24/08/2016
51 Serrano M, Lin AW, McCurrach ME, Beach D, Lowe SW. Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a. Cell. 1997 88(5) 593-602 USA PUBMED JOURNAL PDF 07/03/1997 19.47 3708 190 24/08/2016
52 Fries JF. Aging, natural death and the compression of morbidity. N Engl J Med. 1980 303(3) 130-135 USA PUBMED JOURNAL PDF 01/01/1980 36.64 3687 101 24/08/2016
53 Beckman KB, Ames BN. The free radical theory of aging matures. Physiol Rev. 1998 78(2) 547-81 USA PUBMED JOURNAL PDF 01/04/1998 18.40 4093 222 24/08/2016
54 Wullschleger S, Loewith R, Hall MN. TOR signaling in growth and metabolism. Cell. 2006 124(3) 471-84 Europe (Switzerland) PUBMED JOURNAL PDF 10/02/2006 10.54 3029 287 24/08/2016
55 Schenk D, Barbour R, Dunn W, Gordon G, Grajeda H, Guido T, Hu K, Huang J, Johnson-Wood K, Khan K, Kholodenko D, Lee M, Liao Z, Lieberburg I, Motter R, Mutter L, Soriano F, Shopp G, Vasquez N, Vandevert C, Walker S, Wogulis M, Yednock T, Games D, Seubert P. Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse. Nature. 1999 400(6740) 173-7 USA PUBMED JOURNAL + 08/07/1999 17.13 4093 239 24/08/2016
56 Hachinski VC, Iliff LD, Zilhka E, Du Boulay GH, McAllister VL, Marshall J, Russell RW, Symon L. Cerebral blood flow in dementia. Arch Neurol. 1975 32(9) 632-7 Europe (UK) PUBMED JOURNAL + 01/09/1975 40.98 3277 80 24/08/2016
57 Salthouse TA. The processing-speed theory of adult age differences in cognition. Psychol Rev. 1996 103(3) 403-28 USA PUBMED JOURNAL + 01/07/1996 20.15 3939 195 24/08/2016
58 Whitehouse PJ, Price DL, Struble RG, Clark AW, Coyle JT, Delon MR. Alzheimer‘s disease and senile dementia: Loss of neurons in the basal forebrain. Science. 1982 215(4537) 1237-9 USA PUBMED JOURNAL + 05/03/1982 34.47 3197 93 24/08/2016
59 Walsh DM, Klyubin I, Fadeeva JV, Cullen WK, Anwyl R, Wolfe MS, Rwan MJ, Selkoe DJ. Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo. Nature. 2002 416(6880) 535-9 Europe (Ireland), USA PUBMED JOURNAL PDF 02/04/2002 14.40 3504 243 26/08/2016
60 Davies P, Maloney AJ. Selective loss of central cholinergic neurons in Alzheimer‘s disease. Lancet. 1976 2(8000) 1403 Europe (UK) PUBMED JOURNAL + 25/12/1976 39.67 3179 80 26/08/2016
61 Vassar R, Bennett BD, Babu-Khan S, Kahn S, Mendiaz EA, Denis P, Teplow DB, Ross S, Amarante P, Loeloff R, Luo Y, Fisher S, Fuller J, Edenson S, Lile J, Jarosinski MA, Biere AL, Curran E, Burgess T, Louis JC, Collins F, Treanor J, Rogers G, Citron M. Beta-secretase cleavage of Alzheimer‘s amyloid precursor protein by the transmembrane aspartic protease BACE. Science. 1999 286(5440) 735-41 USA PUBMED JOURNAL + 22/10/1999 16.84 3347 199 26/08/2016
62 Coyle JT, Price DL, DeLong MR. Alzheimer‘s disease: A disorder of cortical cholinergic innervation. Science. 1983 219(4589) 1184-90 USA PUBMED JOURNAL + 11/03/1983 33.46 3310 99 26/08/2016
63 Good CD, Johnsrude IS, Ashburner J, Henson RN, Friston KJ, Frackowiak RS. A voxel-based morphometric study of ageing in 465 normal adult human brains. NeuroImage. 2001 14(1 Pt 1) 21-36 Europe (UK) PUBMED JOURNAL + 01/07/2001 15.15 3468 229 26/08/2016
64 Klein RJ, Zeiss C, Chew EY, Tsai JY, Sackler RS, Haynes C, Henning AK, SanGiovanni JP, Mane SM, Mayne ST, Bracken MB, Ferris FL, Ott J, Barnstable C, Hoh J Complement factor H polymorphism in age-related macular degeneration. Science. 2005 308(5720) 385-9 USA PUBMED JOURNAL + 15/04/2005 11.36 3447 303 26/08/2016
65 Shepherd J, Blauw GJ, Murphy MB, Bollen EL, Buckley BM, Cobbe SM, Ford I, Gaw A, Hyland M, Jukema JW, Kamper AM, Macfarlane PW, Meinders AE, Norrie J, Packard CJ, Perry IJ, Stott DJ, Sweeney BJ, Twomey C, Westendorp RG; PROSPER study group. PROspective Study of Pravastatin in the Elderly at Risk. Pravastatin in elderly individuals at risk of vascular disease (PROSPER): A randomised controlled trial. Lancet. 2002 360(9346) 1623-30 Europe (Ireland, Netherlands, UK) PUBMED JOURNAL + 23/11/2002 13.76 3340 243 26/08/2016
66 Williams GC. Pleiotropy, natural selection and the evolution of senescence. Evolution. 1957 11(4) 398-411 USA PDF 01/04/1957 59.41 3356 56 29/08/2016
67 Rosenfeld PJ, Brown DM, Heier JS, Boyer DS, Kaiser PK, Chung CY, Kim RY; MARINA Study Group. Ranibizumab for neovascular age-related macular degeneration. N Engl J Med. 2006 355(14) 1419-31 USA PUBMED JOURNAL PDF 05/10/2006 9.90 3922 396 29/08/2016
68 Krüger R, Kuhn W, Müller T, Woitalla D, Graeber M, Kösel S, Przuntek H, Epplen JT, Schols L, Riess O. Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson‘s disease. Nat Genet. 1998 18(2) 106-8 Europe (Germany) PUBMED JOURNAL + 01/02/1998 18.57 3150 170 30/08/2016
69 Paffenbarger RS Jr, Hyde RT, Wing AL, Hsieh CC. Physical activity, all-cause mortality, and longevity of college alumni. N Engl J Med. 1986 314(10) 605-13 USA PUBMED JOURNAL + 06/03/1986 30.48 3155 104 30/08/2016
70 Rosen WG, Mohs RC, Davis KL. A new rating scale for Alzheimer‘s disease. Am J Psychiatry. 1984 141(11) 1356-64 USA PUBMED JOURNAL + 01/11/1984 31.83 3141 99 30/08/2016
71 Spear LP. The adolescent brain and age-related behavioral manifestations. Neurosci Biobehav Rev. 2000 24(4) 417-63 USA PUBMED JOURNAL PDF 01/06/2000 16.25 3605 211 30/08/2016
72 Akiyama H, Barger S, Barnum S, Bradt B, Bauer J, Cole GM, Cooper NR, Eikelenboom P, Emmerling M, Fiebich BL, Finch CE, Frautschy S, Griffin WS, Hampel H, Hull M, Landreth G, Lue L, Mrak R, Mackenzie IR, McGeer PL, O‘Banion MK, Pachter J, Pasinetti G, Plata-Salaman C, Rogers J, Rydel R, Shen Y, Streit W, Strohmeyer R, Tooyoma I, Van Muiswinkel FL, Veerhuis R, Walker D, Webster S, Wegrzyniak B, Wenk G, Wyss-Coray T. Inflammation and Alzheimer‘s disease. Neurobiol Aging. 2000 21(3) 383-421 USA PUBMED JOURNAL + 01/05/2000 16.33 3340 205 30/08/2016
73 Chiti F, Dobson CM. Protein misfolding, functional amyloid, and human disease. Annu Rev Biochem. 2006 75 333-66 Europe(Italy, UK) PUBMED JOURNAL + 01/07/2006 10.17 3807 375 31/08/2016
74 Sohal RS, Weindruch R. Oxidative stress, caloric restriction, and aging. Science. 1996 273(5271) 59-63 USA PUBMED JOURNAL + 05/07/1996 20.16 2882 143 31/08/2016
75 Hardy JA, Higgins GA. Alzheimer‘s disease: The amyloid cascade hypothesis. Science. 1992 256(5054) 184-5 USA PUBMED JOURNAL + 10/04/1992 24.39 3426 140 31/08/2016
76 Wallace DC. Mitochondrial diseases in man and mouse. Science. 1999 283(5407) 1482-88 USA PUBMED JOURNAL + 05/03/1999 17.49 2812 161 31/08/2016
77 Stadtman ER. Protein oxidation and aging. Science. 1992 257(5074) 1220-4 USA PUBMED JOURNAL + 28/08/1992 24.01 2781 116 31/08/2016
78 Baur JA, Pearson KJ, Price NL, Jamieson HA, Lerin C, Kalra A, Prabhu VV, Allard JS, Lopez-Lluch G, Lewis K, Pistell PJ, Poosala S, Becker KG, Boss O, Gwinn D, Wang M, Ramaswamy S, Fishbein KW, Spencer RG, Lakatta EG, Le Couteur D, Shaw RJ, Navas P, Puigserver P, Ingram DK, de Cabo R, Sinclair DA. Resveratrol improves health and survival of mice on a high-calorie diet. Nature. 2006 444(7117) 337-42 Australia, USA PUBMED JOURNAL + 16/11/2006 9.79 3267 334 31/08/2016
79 Khachaturian ZS. Diagnosis of Alzheimer‘s disease. Arch Neurol. 1985 42(11) 1097-105 USA PUBMED JOURNAL + 01/11/1985 30.83 2482 81 31/08/2016
80 Sokoloff P, Giros B, Martres MP, Bouthenet ML, Schwartz JC. Molecular cloning and characterization of a novel dopamine receptor (D3) as a target for neuroleptics. Nature. 1990 347(6289) 146-51 Europe (France) PUBMED JOURNAL + 13/09/1990 25.96 2508 97 31/08/2016
81 Terry RD, Masliah E, Salmon DP, Butters N, DeTeresa R, Hill R, Hansen LA, Katzman R. Physical basis of cognitive alterations in Alzheimer‘s disease: Synapse loss is the major correlate of cognitive impairment. Ann Neurol. 1991 30(4) 572-80 USA PUBMED JOURNAL + 01/10/1991 24.92 2885 116 31/08/2016
82 Betarbet R, Sherer TB, MacKenzie G, Garcia-Osuna M, Panov AV, Greenamyre JT. Chronic systemic pesticide exposure reproduces features of Parkinson‘s disease. Nat Neurosci. 2000 3(12) 1301-6 USA PUBMED JOURNAL + 01/12/2000 15.75 2809 178 31/08/2016
83 Berlett BS, Stadtman ER. Protein oxidation in aging, disease, and oxidative stress. J Biol Chem. 1997 272(33) 20313-6 USA PUBMED JOURNAL + 15/08/1997 19.04 2937 154 31/08/2016
84 Howitz KT, Bitterman KJ, Cohen HY, Lamming DW, Lavu S, Wood JG, Zipkin RE, Chung P, Kisielewski A, Zhang LL, Scherer B, Sinclair DA. Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan. Nature. 2003 425(6954) 191-6 USA PUBMED JOURNAL + 11/09/2003 12.97 3045 235 31/08/2016
85 Alzheimer A. Über eine eigenartige Erkrankung der Hirnrinde. Allgemeine Zeitschrift für Psychiatrie und psychisch-gerichtliche Medizin. 1907 64 146-148 Europe (Germany) PDF 01/01/1907 109.66 2778 25 31/08/2016 English translation
(PUBMED JOURNAL PDF )
86 Games D, Adams D, Alessandrini R, Barbour R, Berthelette P, Blackwell C, Carr T, Clemens J, Donaldson T, Gillespie F, et al. Alzheimer-type neuropathology in transgenic mice overexpressing V717F beta-amyloid precursor protein. Nature. 1995 373(6514) 523-7 USA PUBMED JOURNAL + 09/02/1995 21.56 2458 114 31/08/2016
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