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Ageing-related Databases

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Biological Data

Name Description Comments
AgeFactDB - The JenAge Ageing Factor Database AgeFactDB is aimed at the collection and integration of ageing-related data from existing databases and manual or automatic information extraction from the scientific literature. AgeFactDB provides observations on the effect of ageing factors (genes, chemical compounds and other factor such as dietary restriction) on life span and/or ageing phenotype as well as information on the ageing factors itself.
AGEMAP AGEMAP is a gene expression database for aging in mice. It catalogs changes in gene expression for 8,932 genes in 16 tissues as a function of age.
Aging Genes and Interventions Database This is a database on genes and interventions related to aging.
AnAge - The Animal Ageing & Longevity Database AnAge is a curated database of ageing and life history in animals, including extensive longevity records. It was primarily developed for comparative biology studies, in particular studies of longevity and ageing. Part of HAGR (Human Ageing Genomic Resources).
CID - Cross-Species Interactome Database The CISBAN Cross-Species Interactomes Database (CID) integrates interaction data from a range of model organisms used in ageing research. The project has two specific goals. The first is to integrate individual interaction datasets from publicly available data sources for each organism into a weighted probabilistic network. The second is to facilitate comparative interactomics analyses by providing a tool to transfer and compare interaction data between different organisms. The CID Cytoscape Plugin is used to access CID.
DAA - Digital Ageing Atlas The Digital Ageing Atlas (DAA) is a portal of age-related changes covering different biological levels. It integrates molecular, physiological, psychological and pathological age-related data to create an interactive portal that serves as the first centralised collection of human ageing changes and pathologies.
GenAge The Ageing Gene Database GenAge is a curated database of genes related to ageing. GenAge is divided into genes related to longevity and/or ageing in model organisms and ageing-related human genes. Part of HAGR (Human Ageing Genomic Resources).
GenDR The Dietary Restriction Genes Database GenDR is a curated database of genes related to dietary restriction and ageing. Part of HAGR (Human Ageing Genomic Resources).
GeroProtectors Curated database of geroprotectors
iPAD - iNTERNET PRIMATE AGING DATABASE The internet Primate Aging Database (iPAD) is a multi-centered, relational database of biological variables in aging, captive nonhuman primates.
Lifespan Observations Database The Lifespan Observations database contains data on the lifespan effects of interventions by genetic engineering, chemical compounds (e.g.: rapamycin) and environmental effects (e.g.: irradiation) across multiple species. The database is community-driven which means that users are allowed to submit and to edit data.
LongevityMap The Human Longevity Genetic Variants Database LongetivyMap is a curated database of human genetic variants associated with longevity. The LongevityMap contains a repository of genetic association studies of longevity. Part of HAGR (Human Ageing Genomic Resources).
MitoInteractome - Mitochondrial Protein Interactome Database MitoInteractome is a web-based portal containing information on predicted protein-protein interactions, physico-chemical properties, polymorphism, and diseases related to the mitochondrial proteome. It contains several thousand protein sequences which were extracted from the following databases: SwissProt, MitoP, MitoProteome, HPRD and Gene Ontology database.
MITOMAP - A human mitochondrial genome database MITOMAP is a compendium of polymorphisms and mutations of the human mitochondrial DNA. It reports published and unpublished data on human mitochondrial DNA variation, curated manually.
MPD - Mouse Phenome database The Mouse Phenome Database (MPD) is a database of mouse strain characterizations, to facilitate the study and use of laboratory mice in research. It offers general phenotype and genotype information and includes a special section on aging-related studies.
NetAge The NetAge database is a compendium of networks for longevity, age-related diseases and associated processes.
PhenomicDB PhenomicDB is a multi-organism phenotype-genotype database including human, mouse, fruit fly, C.elegans, and other model organisms. The inclusion of gene indices (NCBI Gene) and orthologues from HomoloGene allows to compare phenotypes of a given gene over many organisms simultaneously.
PRIDE - PRoteomics IDEntifications database PRIDE is a centralized, standards compliant, public data repository for proteomics data. It provides protein and peptide identifications together with the evidence supporting these identifications. It is divided into a public and a private section.
REPAIRtoire - A database of DNA repair pathways REPAIRtoire contains components involved in the repair mechanisms of all kinds of cellular DNA lesions. In this version, repair pathways from H.sapiens, E.coli and S.cerevisiae are contained, together with their protein components and molecular events that trigger those pathways.
TMIG-2DPAGE Database The TMIG-2DPAGE Database is a proteome database of cultured human cells. It was developed for the proteomic analysis of molecular mechanisms of aging and age-dependent cell dysfunction. 2D-PAGE images are used as clickable image maps to access the data.

Demographic Data

Further information: Miscellaneous data
Name Description Comments
AGID - AGing Integrated Database AGID is an on-line query system based on AoA(Administration on Aging)-related data files and surveys. Furthermore it includes population characteristics from the U.S. Census Bureau.
European Health for All Database (HFA-DB) HFA-DB provides a selection of core health statistics covering basic demographics, health status, health determinants and risk factors, and health-care resources, utilization and expenditure in the 53 countries in the WHO European Region. It allows queries for country, intercountry, and regional analyses.
GeroStat The statistical information system GeroStat offers gerontological and demographic data from official statistics and from social research.
GGP - Generations & Gender Programme - Contextual Database The Contextual Database of the Generations and Gender Program is a comparative collection of around 200 contextual variables on the national and regional level for each country participating in the international Generations and Gender Program, coordinated by the Population Activities Unit of the United Nation‘s Economic Commission of Europe.
HFD - The Human Fertility Database The Human Fertility Database (HFD) seeks to provide access to detailed, well-documented and high-quality data on period and cohort fertility. The major HFD output includes detailed data on births, unconditional and conditional fertility rates, cohort and period fertility tables as well as selected aggregate indicators such as total fertility rates, mean ages at childbearing, and parity progression ratios.
You must register before you can access the data.
registration necessary
HMD - The Human Mortality Database The Human Mortality Database (HMD) contains original calculations of death rates and life tables for national populations (countries or areas), as well as the input data used in constructing those tables. The input data consist of death counts from vital statistics, plus census counts, birth counts, and population estimates from various sources.
You must register before you can access the data.
registration necessary
Human Life-Table Database The Human Life-Table Database is a collection of population life tables covering a multitude of countries and many years. Most of the HLD life tables are life tables for national populations, which have been officially published by national statistical offices.
IDB - International Data Base The International Data Base (IDB) of the United States Census Bureau provides demographic information (e.g.: population size, fertility, mortality, migration, population pyramids) by country or region over time. The data are also projected into the future.
IDL - International Database on Longevity The International Database on Longevity (IDL) is the result of an ongoing concerted effort to provide thoroughly validated information on individuals who attain extreme ages. The IDL allows for the demographic analysis of mortality at the highest ages. Originally, the data were collected on individuals who attained an age of 110 years or more - so called supercentenarians. In the meantime the data collection has been extended to include younger ages for some countries.
You must register before you can access the data.
registration necessary
K-T database - Kannisto-Thatcher Database on Old Age Mortality The Kannisto-Thatcher database on old age mortality (K-T database) includes data on death counts and population counts classified by sex, age, year of birth, and calendar year for more than 30 countries.
You must register before you can access the data.
registration necessary
Longevity Records "Longevity Records: Life Spans of Mammals, Birds, Amphibians, Reptiles, and Fish" is a book on life spans of a large collection of organisms (Odense Monographs on Population Aging 8, JR Carey & DS Judge, Odense University Press 2001,ISBN 87-7838-539-3, ISSN 0909-119X). The data tables of the book are available and searchable online.
European Mortality Database (MDB) This European mortality database (MDB) contains mortality-related indicators and is a supplement to the generic European health for all database (HFA-DB). The mortality indicators are presented for the selected 67 causes or groups of causes of death by defined age groups.
NACDA - National Archive of Computerized Data on Aging The National Archive of Computerized Data on Aging (NACDA) acquires and preserves data relevant to gerontological research, processing as needed to promote effective research use, disseminates them to researchers, and facilitates their use.
NIA - Population Studies Database The NIA Population Studies Database established by the U.S. National Institute on Aging brings together in one searchable location information about a range of population studies of interest to the research on aging community.
SurvCurv SurvCurv is a database of manually curated and annotated survival data. The database offers various functions including plotting, mathematical models, and statistical tests, facilitating e.g. reanalysis and cross comparisons.

Diseases

Name Description Comments
AlzGene Database (Alzheimer Research Forum) Field synopsis of genetic association studies in Alzheimer‘s Disease.
Alzheimer Disease & Frontotemporal Dementia Mutation Database (AD&FTDMDB) The Alzheimer Disease & Frontotemporal Dementia Mutation Database (AD&FTDMDB) aims at collecting all known mutations and non-pathogenic coding variations in the genes related to Alzheimer disease (AD) and frontotemporal dementia (FTD).
Atlas of Genetics and Cytogenetics in Oncology and Haematology The Atlas of Genetics and Cytogenetics in Oncology and Haematology is a peer reviewed on-line journal and database devoted to genes, cytogenetics, and clinical entities in cancer, and cancer-prone diseases.
International Alzheimer‘s Disease Portfolio (IADRP) The goal of the IADRP project is to enable funding organizations to assess the changing landscape of Alzheimer‘s Disease research and coordinate strategies, leverage resources, and avoid duplication of effort.
Mutation Database for Parkinson‘s Disease (MDPD) MDPD provide access to information about genes related to Parkinson‘s disease.
PDGene Database The PDGene Database aims to provide a comprehensive, unbiased and regularly updated collection of genetic association studies performed in Parkinson‘s disease. It includes summaries of key characteristics of the investigated populations, as well as genotype distributions in cases and controls. It provides continuously updated random-effects meta-analyses for polymorphisms with genotype data in at least three case-control samples.
The Silver Book The Silver Book is an almanac of thousands of facts, statistics, graphs, and data from hundreds of agencies, organizations, and experts. It is a searchable database, produced and updated by the Alliance for Aging Research, that provides free and easy access to the latest information on the burden of chronic diseases that disproportionately impact older Americans, and the value of investing in medical research.

Metadata

Name Description Comments
AgeInfo AgeInfo is an information service about old age and ageing. It includes a bibliographic database, detailed information about organisations active in the field of Old Age and Ageing and an international Calendar of Events (courses, conferences, meetings, training sessions, etc.).
Data access requires a payment.
access restricted
AgeLine AgeLine covers the literature of social gerontology and includes aging-related content from the health sciences, psychology, sociology, social work, economics, and public policy. It indexes over 600 journals, books, book chapters, reports, dissertations, consumer guides, and educational videos.
Data access requires a payment.
access restricted
AgeStats and - AgeSource Worldwide These two databases have been created by AARP (American Associationof Retired Persons) to facilitate the international exchange of policy and program-relevant information in aging.

AgeSource Worldwide identifies several hundred information resources in some 25 countries which are significant either in size or in their unique coverage of particular aging-related issues. The resources include, among others, clearinghouses, libraries, databases, training modules, major reports, and Web metasites.

AgeStats Worldwide provides access to comparative statistical data that compare the situation of older adults across countries or regions around a variety of issues areas. The most recent data and projections as far ahead as 2060 are provided where available.

CDC Wonder The WONDER (Wide-ranging Online Data for Epidemiologic Research) online databases makes the information resources of the Centers for Disease Control and Prevention (CDC) available to public health professionals and the public at large. It provides access to a wide array of public health information and utilize a rich ad-hoc query system for the analysis of public health data.
ERA-AGE Database The ERA-AGE database contains information about European research on ageing.
IARP - International Aging Research Portfolio Database The IARP database contains detailed information about ageing research projects worldwide. It includes for instance funding information, the project description and related publications.
NDAR - National Database of Ageing Research NDAR, the National Database of Ageing Research, is the Centre for Policy on Ageing‘s database of research into ageing and older people. The focus is on current and ongoing research. The resource was originally established in 1955 as ‘old age: a register of social research‘.
Shared Ageing Research Models (ShARM UK) The network of live ageing colonies is a database of the colonies currently held by investigators willing to release surplus tissues at the time of harvest. This enables those requiring tissues to collect and process tissues according to their individual need. PUBMED