Ageing-related Papers

Highly Cited Papers on Ageing and Age-related Diseases
Collection of Historical and Current Papers on Ageing and Age-Related Diseases

Highly Cited Papers on Ageing and Age-related Diseases

Note: This compilation is work in progress. Please email us (jsuehnel@fli-leibniz.de) if you are aware of papers that should be included in the list. Currently, our lower limit is either a total number of 1000 citations or a number of 100 citations per year according to Google Scholar (GS). We have also analyzed the Web of Science (WoS) data but are obviously not allowed to make these data freely accessible according to the Thomson Reuters policy. Except for very few cases the number of GS citations is higher than the related WoS value. To get a more quantitative impression have a look on a plot of the correlation between GS and WoS data. The Date of Publication was obtained from PubMed. For older publications only the month is indicated. In this case the 1st day of the corresponding month was used. The Time Since Publication was calculated using Wolfram Alpha.

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#	Author(s)	Title	Journal	Year	Volume	Pages	Subscription Required	Publication Date	Time Since Publication (Years)	Times Cited - Total (Google Scholar)	Times Cited - Per Year (Google Scholar)	Date of Analysis
1	McKhann G, Drachman D, Folstein M, Katzman R, Price D, Stadlan EM.	Clinical diagnosis of Alzheimer‘s disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer‘s Disease.	Neurology	1984	34(7)	939-44		01/07/1984	27.41	15703	573	29/11/2011
2	Kim NW, Piatyszek MA, Prowse KR, Harley CB, West MD, Ho PL, Coviello GM, Wright WE, Weinrich SL, Shay JW.	Specific association of human telomerase activity with immortal cells and cancer.	Science	1994	266(5193)	2011-5	+	23/12/1994	16.93	5538	327	29/11/2011
3	Hoehn MM, Yahr MD.	Parkinsonism: onset, progression and mortality.	Neurology	1967	17(5)	427-42		01/05/1967	44.58	5158	116	29/11/2011
4	Braak H, Braak E.	Neuropathological stageing of Alzheimer-related changes.	Acta Neuropathol.	1991	82(4)	239-59		01/04/1991	20.66	5122	248	29/11/2011
5	Hardy J, Selkoe DJ.	The amyloid hypothesis of Alzheimer‘s Disease: Progress and problems on the road to therapeutics.	Science	2002	297(5580)	353-6	+	19/07/2002	9.36	4208	449	29/11/2011
6	Ames BN, Shigenaga MK, Hagen TM.	Oxidants, antioxidants and the degenerative diseases of aging.	Proc Natl Acad Sci U S A.	1993	90(17)	7915-22		01/09/1993	18.24	4206	231	29/11/2011
7	Murray CJ, Lopez AD.	Alternative projections of mortality and disability by cause 1990-2020: Global burden of disease study.	Lancet	1997	10(5)	594-605		24/05/1997	14.52	4049	278	29/11/2011
8	Hayflick L, Moorhead PS.	The serial cultivation of human diploid cell strains.	Exp Cell Res.	1961	25	585-621		01/12/1961	49.99	4004	80	29/11/2011
9	Harman D.	Aging: a theory based on free radical and radiation chemistry.	J Gerontol.	1956	11(3)	298-300		01/07/1956	55.42	3938	71	30/11/2011
10	Bartus RT, Dean RL 3rd, Beer B, Lippa AS.	The cholinergic hypothesis of geriatric memory dysfunction.	Science	1982	217(4558)	408-14	+	30/07/1982	29.33	3827	130	29/11/2011
11	Polymeropoulos MH, Lavedan C, Leroy E, Ide SE, Dehejia A, Dutra A, Pike B, Root H, Rubenstein J, Boyer R, Stenroos ES, Chandrasekharappa S, Athanassiadou A, Papapetropoulos T, Johnson WG, Lazzarini AM, Duvoisin RC, Di Iorio G, Golbe LI, Nussbaum RL.	Mutation in the alpha-synuclein identified in families with Parkinson‘s disease.	Science	1997	276(5321)	2045-7	+	27/06/1997	14.42	3711	257	29/11/2011
12	Droege W.	Free radicals in the physiological control of cell function.	Physiol Rev.	2002	82(1)	47-95		01/01/2002	9.91	3530	356	30/11/2011
13	Kang J, Lemaire HG, Unterbeck A, Salbaum JM, Masters CL, Grzeschik KH, Multhaup G, Beyreuther K, Müller-Hill B	The precursor of Alzheimer‘s disease amyloid A4 protein resembles a cell-surface receptor.	Nature	1987	325(6106)	733-6	+	19/02/1987	24.78	3502	141	29/11/2011
14	Hayflick L.	The limited in vitro lifetime of human diploid cell strains.	Exp Cell Res.	1965	37	614-36		01/03/1965	46.75	3427	73	30/11/2011
15	Bodnar AG, Ouellette M, Frolkis M, Holt SE, Chiu CP, Morin GB, Harley CB, Shay JW, Lichtsteiner S, Wright WE.	Extension of life-span by introduction of telomerase into normal human cells.	Science	1998	279(5349)	349-52	+	16/01/1998	13.87	3407	246	30/11/2011
16	Harley CB, Futcher AB,Greider CW.	Telomeres shorten during aging of human fibroblasts.	Nature	1990	345(6274)	458-60	+	31/05/1990	21.50	3305	154	30/11/2011
17	Glenner GG, Wong CW.	Alzheimer‘s disease: initial report of the purification and characterization of a novel cerebrovascular amyloid protein.	Biochem Biophys Res Commun.	1984	120(3)	885-90		16/05/1984	27.54	3244	118	30/11/2011
18	Finkel T, Holbrook NJ.	Oxidants, oxidative stress and the biology of ageing.	Nature	2000	408(6809)	239-47	+	09/11/2000	11.06	3170	287	01/12/2011
19	Selkoe DJ.	Alzheimer‘s disease: genes, proteins, and therapy.	Physiol Rev.	2001	81(2)	741-66		01/04/2001	10.67	3117	292	30/11/2011
20	Goate A, Chartier-Harlin MC, Mullan M, Brown J, Crawford F, Fidani L, Giuffra L, Haynes A, Irving N, James L, Mant R, Newton P, Rooke K, Roques P, Talbot C, Pericak-Vance M, Roses A, Williamson R, Rossor M, Owen M, Hardy J	Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer‘s Disease	Nature	1991	349(6311)	704-6	+	21/02/1991	20.77	3025	126	30/11/2011
21	Dimri GP, Lee X, Basile G, Acosta M, Scott G, Roskelley C, Medrano EE, Linskens M, Rubelj I, Pereira-Smith O, Peacocke M, Campisi J.	A biomarker that identifies senescent human cells in culture and in aging skin in vivo.	Proc Natl Acad Sci U S A	1995	92(20)	9363-7		26/09/1995	16.18	2961	183	01/12/2011
22	Ames BN.	Dietary carcinogens and anticarcinogens. Oxygen radicals and degenerative diseases.	Science	1983	22(4617)	256-64	+	23/09/1983	28.19	2730	97	01/12/2011
23	Strittmatter WJ, Saunders AM, Schmechel D, Pericak-Vance M, Enghild J, Salvesen GS, Roses AD.	Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease.	Proc Natl Acad Sci U S A.	1993	90(5)	1977-81		01/03/1993	18.75	2694	144	01/12/2011
24	Lindahl T.	Instability and decay of the primary structure of DNA.	Nature	1993	362(6422)	709-15	+	22/04/1993	18.61	2676	144	01/12/2011
25	Fries SF.	Aging, natural death and the compression of morbidity.	N Engl J Med.	1980	303(3)	130-135		01/01/1980	31.92	2433	76	01/12/2011
26	Good CD, Johnsrude IS, Ashburner J, Henson RN, Friston KJ, Frackowiak RS.	A voxel-based morphometric study of ageing in 465 normal adult human brains.	NeuroImage	2001	14(1 Pt 1)	21-36		01/07/2001	10.42	2359	226	01/12/2011
27	Beckman KB, Ames BN.	The free radical theory of aging matures.	Physiol Rev.	1998	78(2)	547-81		01/04/1998	13.67	2342	171	01/12/2011
28	Serrano M, Lin AW, McCurrach ME, Beach D, Lowe SW.	Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a.	Cell	1997	88(5)	593-602		07/03/1997	14.74	2338	157	01/12/2011
29	Petersen RC, Doody R, Kurz A, Mohs RC, Morris JC, Rabins PV, Ritchie K, Rossor M, Thal L, Winblad B.	Current concepts in mild cognitive impairment.	Arch Neurol.	2001	58(12)	1985-92	+	01/12/2001	10.00	2140	214	01/12/2011
30	Williams GC.	Pleiotropy, natural selection and the evolution for senescence.	Evolution	1957	11(4)	398-411		01/04/1957	54.67	2084	38	01/12/2011
31	Walsh DM, Klyubin I, Fadeeva JV, Cullen WK, Anwyl R, Wolfe MS, Rwan MJ, Selkoe DJ.	Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo.	Nature	2002	416(6880)	535-9		02/04/2002	9.67	2060	213	01/12/2011
32	Sohal RS, Weindruch R.	Oxidative stress, caloric restriction, and aging.	Science	1996	273(5271)	59-63		05/07/1996	15.41	1989	129	01/12/2011
33	Stadtman ER.	Protein oxidation and aging	Science	1982	257(5074)	1220-4	+	28/08/1982	29.27	1989	68	05/12/2011
34	Wallace DC.	Mitochondrial diseases in man and mouse.	Science	1999	283(5407)	1482-88	+	05/03/1999	12.74	1912	150	01/12/2011
35	Klein RJ, Zeiss C, Chew EY, Tsai JY, Sackler RS, Haynes C, Henning AK, SanGiovanni JP, Mane SM, Mayne ST, Bracken MB, Ferris FL, Ott J, Barnstable C, Hoh J	Complement factor H polymorphism in age-related macular degeneration.	Science	2005	308(5720)	385-9		15/04/2005	6.63	1904	287	01/12/2011
36	Wullschleger S, Loewith R, Hall MN	TOR signaling in growth and metabolism.	Cell	2006	124(3)	471-84		10/02/2006	5.81	1811	312	01/12/2011
37	Kuhn HG, Dickinson-Anson H, Gage FH.	Neurogenesis in the dentate gyrus of the adult rat: age-related decrease of neuronal progenitor proliferation.	J Neurosci.	1996	16(6)	2027-33		15/03/1996	15.71	1662	106	01/12/2011
38	Counter CM, Avilon AA, LeFeuvre CE, Stewart NG, Greider CW, Bacchetti S.	Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity.	EMBO J.	1992	11(5)	1921-9		01/05/1992	19.58	1647	84	01/12/2011
39	Haass C, Schlossmacher MG, Hung AY, Vigo-Pelfrey C, Mellon A, Ostaszewski BL, Lieberburg I, Koo EH, Schenk D, Teplow DB, Selkoe DJ.	Amyloid beta-peptide is produced by cultured cells during normal metabolism.	Nature	1992	359(6393)	322-5	+	24/09/1992	19.19	1570	82	01/12/2011
40	Alzheimer A. [Stelzmann RA, Schnitzlein HA, Murtagh FR.]	Über eine eigenartige Erkrankung der Hirnrinde [On an Unusual Illness of the Cerebral Cortex]	Allgemeine Zeitschrift für Psychiatrie und psychisch-gerichtliche Medizin [Clin. Anat.]	1907 [1995]	64 [8]	146-148 [429-431]		01/01/1907	104.92	1549	15	01/12/2011
41	Allsopp RC, Vaziri H, Patterson C, Goldstein S, Younglai EV, Futcher AB, Greider CW, Harley CB.	Telomere length predicts replicative capacity of human fibroblasts.	Proc Natl Acad Sci U S A.	1992	89(21)	10114-8		01/11/1992	19.08	1514	79	01/12/2011
42	Selkoe DJ.	The molecular pathology of Alzheimer‘s disease.	Neuron	1991	6(4)	487-98		01/04/1991	20.67	1494	72	01/12/2011
43	Sapolsky RM, Krey LC, McEwen BS.	The neuroendocrinology of stress and aging: the glucocorticoid cascade hypothesis.	Endocr Rev.	1986	7(3)	284-301	+	01/08/1986	25.33	1448	7	01/12/2011
44	Wolfe MS, Xia W, Ostaszewski BL, Diehl TS, Kimberly WT, Selkoe DJ.	Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity.	Nature	1999	398(6727)	513-7	+	08/04/1999	12.66	1425	113	05/12/2011
45	Imai S, Armstrong CM, Kaeberlein M, Guarente L.	Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase.	Nature.	2000	403(6771)	795-800	+	17/02/2000	11.79	1407	119	01/12/2011
46	Baur JA, Pearson KJ, Price NL, Jamieson HA, Lerin C, Kalra A, Prabhu VV, Allard JS, Lopez-Lluch G, Lewis K, Pistell PJ, Poosala S, Becker KG, Boss O, Gwinn D, Wang M, Ramaswamy S, Fishbein KW, Spencer RG, Lakatta EG, Le Couteur D, Shaw RJ, Navas P, Puigserver P, Ingram DK, de Cabo R, Sinclair DA.	Resveratrol improves health and survival of mice on a high-calorie diet.	Nature	2006	444(7117)	337-42	+	16/11/2006	5.04	1405	279	01/12/2011
47	Shigenaga MK, Hagen TM, Ames BN.	Oxidative damage and mitochondrial decay in aging.	Proc Natl Acad Sci U S A.	1994	91(23)	10771-8		08/11/1994	17.06	1386	81	01/12/2011
48	Kenyon C, Chang J, Gensch E, Rudner A, Tabtiang R.	A C. elegans mutant that lives twice as long as wild-type.	Nature	1993	366(6454)	461-4	+	02/12/1993	18.02	1383	77	08/12/2011
49	Howitz KT, Bitterman KJ, Cohen HY, Lamming DW, Lavu S, Wood JG, Zipkin RE, Chung P, Kisielewski A, Zhang LL, Scherer B, Sinclair DA.	Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan.	Nature	2003	425(6954)	191-6	+	11/09/2003	8.22	1367	166	01/12/2011
50	Harman D.	The aging process.	Proc Natl Acad Sci U S A.	1981	78(11)	7124-8		01/11/1981	30.08	1360	45	01/12/2011
51	Selkoe DJ.	Alzheimer‘s disease is a synaptic failure.	Science	2002	298(5594)	789-91	+	25/10/2002	9.10	1355	149	01/12/2011
52	Citron M, Oltersdorf T, Haass C, McConlogue L, Hung AY, Seubert P, Vigo-Pelfrey C, Lieberburg I, Selkoe DJ.	Mutation of the beta-amyloid precursor protein in familial Alzheimer‘s disease increases beta-protein production.	Nature	1992	360(6405)	672-4	+	17/12/1992	18.96	1273	67	01/12/2011
53	Morgan D, Diamond DM, Gottschall PE, Ugen KE, Dickey C, Hardy J, Duff K, Jantzen P, DiCarlo G, Wilcock D, Connor K, Hatcher J, Hope C, Gordon M, Arendash GW.	A beta peptide vaccination prevents memory loss in an animal model of Alzheimer‘s disease.	Nature	2000	408(6815)	982-5	+	21/12/2000	10.95	1255	115	01/12/2011
54	Fearnley JM, Lees AJ.	Ageing and Parkinson‘s disease: substantia nigra regional selectivity.	Brain	1991	114(Pt. 5)	2283-301		01/10/1991	20.17	1254	62	01/12/2011
55	Yu CE, Oshima J, Fu YH, Wijsman EM, Hisama F, Alisch R, Matthews S, Nakura J, Miki T, Ouais S, Martin GM, Mulligan J, Schellenberg GD.	Positional cloning of the Werner‘s syndrome gene.	Science	1996	272(5259)	258-62	+	12/04/1996	15.64	1235	79	01/12/2011
56	Kimura KD, Tissenbaum HA, Liu Y, Ruvkun G.	daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans.	Science	1997	277(5328)	942-6	+	15/08/1997	14.32	1182	83	08/12/2011
57	Ogg S, Paradis S, Gottlieb S, Patterson GI, Lee L, Tissenbaum HA, Ruvkun G.	The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans.	Nature	1997	389(6654)	994-9	+	30/10/1997	14.11	1132	73	08/12/2011
58	Wallace DC.	A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evolutionary medicine.	Annu Rev Genet.	2005	39	359-407	+	01/01/2005	6.93	1050	152	07/12/2011
59	Martin GM, Sprague CA, Epstein CJ.	Replicative life-span of cultivated human cells. Effects of donor‘s age, tissue, and genotype.	Lab Invest.	1970	23(1)	86-92	+	07/02/2002	9.83	1028	105	08/12/2011
60	Wallace DC.	Mitochondrial genetics - a paradigm for aging and degenerative diseases?	Science	1992	256(5057)	628-32	+	01/05/1992	19.6	1022	52	08/12/2011
61	Warburton DE, Nicol CW, Bredin SS.	Health benefits of physical activity: the evidence.	CMAJ	2006	174(6)	801-9		14/03/2006	5.72	964	169	01/12/2011
62	Trifunovic A, Wredenberg A, Falkenberg M, Spelbrink JN, Rovio AT, Bruder CE, Bohlooly-Y M, Gidlöf S, Oldfors A, Wibom R, Törnell J, Jacobs HT, Larsson NG.	Premature ageing in mice expressing defective mitochondrial DNA polymerase.	Nature	2004	429(6990)	417-23	+	27/05/2004	7.51	944	126	01/12/2011
63	Campisi J.	Senescent cells, tumor suppression, and organismal aging: Good citizens, bad neighbors.	Cell	2005	120(4)	513-22		25/02/2005	6.76	940	139	01/12/2011
64	Harrison DE, Strong R, Sharp ZD, Nelson JF, Astle CM, Flurkey K, Nadon NL, Wilkinson JE, Frenkel K, Carter CS, Pahor M, Javors MA, Fernandez E, Miller RA.	Rapamycin fed late in life extends lifespan in genetically heterogeneous mice	Nature	2009	460(7253)	392-5	+	16/07/2009	2.38	452	190	01/12/2011

Collection of Historical and Current Papers on Ageing and Age-Related Diseases

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Author(s)	Title	Journal	Year	Volume	Pages	Subscription Required	Times Cited (Google Scholar)	Date of Analysis	Comments
Calabrese EJ, Iavicoli I, Calabrese V.	Hormesis; why it is important to biogerontologists.	Biorerontology	2012	Jan 24	Epub ahead of print.	+
Rando TA, Chang HY.	Aging, rejuvenation, and epigenetic reprogramming: resetting the aging clock.	Cell	2012	148(1-2)	46-57	+
Alavez S, Vantipalli MC, Zucker DJ, Klang IM, Lithgow GJ.	Amyloid-binding compounds maintain protein homeostasis during ageing and extend lifespan.	Nature	2011	472(7342)	226-9	+
Bloss CS, Pawlikowska L, Schork NJ.	Contemporary human genetic strategies in aging research.	Ageing Res Rev.	2011	10(2)	191-200	+
Caballero A, Ugidos A, Liu B, Oling D, Kvint K, Hao X, Mignat C, Nachin L, Molin M, Nyström T.	Absence of mitochondrial translation control proteins extends life span by activating sirtuin-dependent silencing.	Mol Cell	2011	42(3)	390-400	+
Donate LE, Blasco MA.	Telomeres in cancer and ageing.	Philos Trans R Soc Lond B Biol Sci.	2011	366(1561)	76-84
Evans DS, Kapahi P, Hsueh WC, Kockel L.	TOR signaling never gets old: Aging, longevity and TORC1 activity.	Ageing Res Rev.	2011	10(2)	225-37	+
Finkel T.	Signal transduction by reactive oxygen species.	J Cell Biol.	2011	194(1)	7-15
Jaskelioff M, Muller FL, Paik JH, Thomas E, Jiang S, Adams AC, Sahin E, Kost-Alimova M, Protopopov A, Cadiñanos J, Horner JW, Maratos-Flier E, Depinho RA.	Telomerase reactivation reverses tissue degeneration in aged telomerase-deficient mice.	Nature	2011	469(7328)	102-6	+
Kriete A, Lechner M, Clearfield D, Bohmann D.	Computational systems biology of aging.	Wiley Interdiscip Rev Syst Biol Med.	2011	3(4)	414-28	+
Kenyon C.	The first long-lived mutants: discovery of the insulin/IGF-1 pathway for ageing.	Philos Trans R Soc Lond B Biol Sci.	2011	366(1561)	9-16
Koga H, Kaushik S, Cuervo AM.	Protein homeostasis and aging: The importance of exquisite quality control.	Ageing Res Rev.	2011	10(2)	205-15	+
Miller RA, Williams JB, Kiklevich JV, Austad S, Harper JM.	Comparative cellular biogerontology: Primer and prospectus.	Ageing Res Rev.	2011	10(2)	181-90	+
Montano M, Long K.	RNA surveillance-An emerging role for RNA regulatory networks in aging.	Ageing Res Rev.	2011	10(2)	216-22	+
Partridge L, Thornton J, Bates G.	The new science of ageing.	Philos Trans R Soc Lond B Biol Sci.	2011	366(1561)	6-8
Partridge L.	Some highlights on research of aging with invertebrates. 2010.	Aging Cell	2011	10(1)	5-9	+
Sahin E, Colla S, Liesa M, Moslehi J, Müller FL, Guo M, Cooper M, Kotton D, Fabian AJ, Walkey C, Maser RS, Tonon G, Foerster F, Xiong R, Wang YA, Shukla SA, Jaskelioff M, Martin ES, Heffernan TP, Protopopov A, Ivanova E, Mahoney JE, Kost-Alimova M, Perry SR, Bronson R, Liao R, Mulligan R, Shirihai OS, Chin L, DePinho RA.	Telomere dysfunction induces metabolic and mitochondrial compromise.	Nature	2011	470(7334)	359-65
Selman C, Withers DJ.	Mammalian models of extended healthy lifespan.	Philos Trans R Soc Lond B Biol Sci.	2011	366(1561)	99-107
Tranah GJ	Mitochondrial-nuclear epistasis: Implications for human aging and longevity.	Ageing Res Rev.	2011	10(2)	238-52	+
Wieser D, Papatheodorou I, Ziehm M, Thornton JM.	Computational biology for ageing.	Philos Trans R Soc Lond B Biol Sci.	2011	366(1561)	51-63
Zhai et al.	Eight common genetic variants associated with serum DHEAS levels suggest a key role in ageing mechanisms.	PLoS Genet.	2011	7(4)
Ziv E, Hu D.	Genetic variation in insulin/IGF-1 signaling pathways and longevity.	Ageing Res Rev.	2011	10(2)	201-4	+
Bishop NA, Lu T, Yankner BA.	Neural mechanisms of ageing and cognitive decline.	Nature	2010	464(7288)	529-35
Bratic I, Trifunovic A.	Mitochondrial energy metabolism and ageing.	Biochim Biophys Acta	2010	1797	961-67	+
Colman RJ, Anderson RM, Johnson SC, Kastman EK, Kosmatka KJ, Beasley TM, Allison DB, Cruzen C, Simmons HA, Kemnitz JW, Weindruch R.	Caloric restriction delays disease onset and mortality in rhesus monkeys.	Science	2010	325(5937)	210-4	+
Coppé JP, Desprez PY, Krtolica A, Campisi J.	The senescence-associated secretory phenotype: the dark side of tumor suppression.	Annu Rev Pathol.	2010	5	99-118	+
Fontana L, Partridge B, Longo VD.	Extending healthy lifespan - from yeast to humans.	Science	2010	328(5976)	321-6	+			Letters on this article
Haigis MC, Yankner BA.	The aging of stress response.	Mol Cell	2010	40(2)	333-44.		31	28/02/2012
Kaeberlein M.	Lessons on longevity from budding yeast.	Nature	2010	464(7288)	513-9
Kenyon CJ.	The genetics of ageing.	Nature	2010	464(7288)	504-12
Lapointe J, Hekimi S.	When a theory of aging ages badly.	Cell Mol Life Sci.	2010	67(1)	1-8
de Lencastre A, Pincus Z, Zhou K, Kato M, Lee SS, Slack FJ.	MicroRNAs both promote adn antagonize longevity in C. elegans.	Curr Biol.	2010	20(24)	2159-68.
de Magalhães JP, Finch CE, Janssens G.	Next-generation sequencing in aging research: Emerging applications, problems, pitfalls and possible solutions.	Ageing Res Rev.	2010	9	315-23	+
Partridge L.	The new biology of ageing.	Philos Trans R Soc Lond B Biol Sci.	2010	365(1537)	147-54		25	05/12/2011
Ristow M, Zarse K.	How increased oxidative stress promotes longevity and metabolic health: The concept of mitochondrial hormesis (mitohormesis).	Exp Gerontol.	2010	45	410-8	+	56	05/12/2011
Sahin E, DePinho RA.	Linking functional decline of telomeres, mitochondria and stem cells during ageing.	Nature	2010	464(7288)	520-28		98	05/12/2011
Sebastiani P, Solovieff N, Puca A, Hartley SW, Melista E, Andersen S, Dworkis DA, Wilk JB, Myers RH, Steinberg MH, Montano M, Baldwin CT, Perls TT.	Genetic signatures of exceptional longevity in humans.	Science	2010	Nov 11. [Epub ahead of print]		+	41	05/12/2011	Supporting material ; the paper was retracted on July 22, 2011.
Vaupel JW.	Biodemography of human ageing.	Nature	2010	464(7288)	536-542		62	05/12/2011
Bates DJ, Liang R, Li N, Wang E.	The impact of noncoding RNA on the biochemical and molecular mechanisms of aging.	Biochim. Biophys. Acta	2009	1790(10)	970-9	+	10	05/12/2011
Blagosklonny MV, Campisi J, Sinclair DA.	Aging: past, present future.	Aging	2009	1(1)	1-5		16	05/12/2011
Calado RT, Young NS.	Telomere diseases.	N Engl J Med.	2009	361(24)	2353-65	+	92	05/12/2011
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Rous P.	The influence of diet on transplanted and spontaneous mouse tumors.	J Exp Med.	1914	20(5)	433-51		130	24/02/2011	Since most cancers occur later in life this finding is related to ageing
Alzheimer A.	Über eigenartige Krankheitsfälle des späteren Alters.	Zeitschrift für die gesamte Neurologie und Psychiatrie	1911	4	356-385		184	24/02/2011
Alzheimer A. [Stelzmann RA, Schnitzlein HA, Murtagh FR.]	Über eine eigenartige Erkrankung der Hirnrinde [On an Unusual Illness of the Cerebral Cortex]	Allgemeine Zeitschrift für Psychiatrie und psychisch-gerichtliche Medizin [Clin. Anat.]	1907 [1995]	64 [8]	146-148 [429-431]		1549	01/12/2011	English translation
Parkinson J.	Essay on the shaking palsy	Publisher Whittington and Rowland	1817